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环境抗生素污染的微生物修复进展
引用本文:吴迎,冯朋雅,李荣,陈潇,李祥锴,TAWATCHAI SUMPRADIT,刘璞.环境抗生素污染的微生物修复进展[J].生物工程学报,2019,35(11):2133-2150.
作者姓名:吴迎  冯朋雅  李荣  陈潇  李祥锴  TAWATCHAI SUMPRADIT  刘璞
作者单位:兰州大学 细胞活动与逆境适应教育部重点实验室,甘肃 兰州 730000,兰州大学 细胞活动与逆境适应教育部重点实验室,甘肃 兰州 730000,兰州大学 细胞活动与逆境适应教育部重点实验室,甘肃 兰州 730000,兰州大学 细胞活动与逆境适应教育部重点实验室,甘肃 兰州 730000,兰州大学 细胞活动与逆境适应教育部重点实验室,甘肃 兰州 730000,兰州大学 细胞活动与逆境适应教育部重点实验室,甘肃 兰州 730000,兰州大学 细胞活动与逆境适应教育部重点实验室,甘肃 兰州 730000
基金项目:兰州大学中央高校基本科研业务费专项资金 (No. lzujbky-2018-105) 资助。
摘    要:近年来随着抗生素在畜牧业、水产养殖业以及医疗行业的广泛应用,大量抗生素通过排泄物进入环境,导致我国大面积水体及土壤环境中抗生素残留量急剧增高。环境中不同种类的抗生素的残留导致微生物种群结构失衡,对生态环境及人类造成极大危害。因此,解决抗生素残留问题是21世纪新型环境污染物领域的一个重要课题。已有研究显示,一些微生物能够以抗生素为碳源生存,可用于降解环境中残留抗生素,但人们对微生物降解抗生素的降解机制了解较少。文中概括了近十年来抗生素降解菌株和菌群对抗生素的去除情况,以及应用微生物菌群处理抗生素残留的技术方法,同时对未来利用微生物修复法减少环境中抗生素残留进行了展望。

关 键 词:抗生素,生物降解,菌株,微生物群落,合成生物学
收稿时间:2019/4/25 0:00:00

Progress in microbial remediation of antibiotic-residue contaminated environment
Ying Wu,Pengya Feng,Rong Li,Xiao Chen,Xiangkai Li,TAWATCHAI SUMPRADIT and Pu Liu.Progress in microbial remediation of antibiotic-residue contaminated environment[J].Chinese Journal of Biotechnology,2019,35(11):2133-2150.
Authors:Ying Wu  Pengya Feng  Rong Li  Xiao Chen  Xiangkai Li  TAWATCHAI SUMPRADIT and Pu Liu
Institution:Key Laboratory of Cell Activity and Stress Adaptation, Lanzhou University, Lanzhou 730000, Gansu, China,Key Laboratory of Cell Activity and Stress Adaptation, Lanzhou University, Lanzhou 730000, Gansu, China,Key Laboratory of Cell Activity and Stress Adaptation, Lanzhou University, Lanzhou 730000, Gansu, China,Key Laboratory of Cell Activity and Stress Adaptation, Lanzhou University, Lanzhou 730000, Gansu, China,Key Laboratory of Cell Activity and Stress Adaptation, Lanzhou University, Lanzhou 730000, Gansu, China,Key Laboratory of Cell Activity and Stress Adaptation, Lanzhou University, Lanzhou 730000, Gansu, China and Key Laboratory of Cell Activity and Stress Adaptation, Lanzhou University, Lanzhou 730000, Gansu, China
Abstract:In recent years, antibiotics have been widely used in animal husbandry, aquaculture and the medication in China. Many antibiotics are discharged into the environment, resulting in dramatic increase of antibiotic residues in domestic water and soil. Residues of different antibiotics in the environment change the microbial structure, which is extremely harmful to the ecological environment and humans. Therefore, remediation of antibiotic contamination is significantly important. Studies have shown that some microorganisms can degrade and utilize antibiotics, and thus have good application prospects on bioremediation of antibiotic contamination. However, little is known about the microbial degradation mechanism of antibiotics. This article summarizes the removal of antibiotics by antibiotic-degrading strains and bacterial flora in recent ten years, and the methods of using microbial flora to treat antibiotic residues. The future prospect of using microbial remediation to reduce antibiotic residues in the environment has also been discussed.
Keywords:antibiotics  biodegradation  strains  microbial communities  synthetic biology
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