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光合微生物混菌体系的应用和研究进展
引用本文:张丽,宋馨宇,陈磊,张卫文.光合微生物混菌体系的应用和研究进展[J].生物工程学报,2020,36(4):652-665.
作者姓名:张丽  宋馨宇  陈磊  张卫文
作者单位:1 天津大学 化工学院合成微生物学实验室,天津 300072;2 教育部合成生物学前沿研究中心,天津 300072;3 教育部系统生物工程重点实验室,天津 300072;1 天津大学 化工学院合成微生物学实验室,天津 300072;2 教育部合成生物学前沿研究中心,天津 300072;3 教育部系统生物工程重点实验室,天津 300072;4 天津大学 生物安全战略研究中心,天津 300072
基金项目:国家重点研发计划 (No. 2018YFA0903000),国家自然科学基金 (Nos. 31901016, 31770100, 91751102, 21621004, 31370115, 31470217, 31972931) 资助。
摘    要:光合微生物与其他异养微生物混菌共培养是近年来的研究热点,该体系弥补了光合微生物纯培养时易染菌、不稳定等缺陷,在污水处理、土壤改善、生物降解有害物质、生产高附加值产物方面拥有广阔的应用前景。文中通过系统总结天然和人工光合微生物混菌体系的研究进展,探究人工构建的光驱动混菌体系的基础理论和应用前景,为进一步利用合成生物学等前沿技术理性改造基于光合微生物的混菌培养系统提供科学依据。

关 键 词:光合微生物  混菌体系  环境工程  细胞工厂  相互作用
收稿时间:2019/6/29 0:00:00

Recent progress in photosynthetic microbial co-culture systems
Li Zhang,Xinyu Song,Lei Chen,Weiwen Zhang.Recent progress in photosynthetic microbial co-culture systems[J].Chinese Journal of Biotechnology,2020,36(4):652-665.
Authors:Li Zhang  Xinyu Song  Lei Chen  Weiwen Zhang
Institution:1 Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, China;2 Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, China;3 Collaborative Innovation Center of Chemical Science and Engineering, Tianjin 300072, China;1 Laboratory of Synthetic Microbiology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, China;2 Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering, Ministry of Education of China, Tianjin 300072, China;3 Collaborative Innovation Center of Chemical Science and Engineering, Tianjin 300072, Chinal;4 Center for Biosafety Research and Strategy, Tianjin University, Tianjin 300072, China
Abstract:Co-culture systems consisted of photosynthetic microorganisms and others heterotrophic microbes have attracted great attention in recent years. These systems show many advantages when compared with single culture grown under autotrophic conditions, such as less vulnerable to pollution and more stability, thus have been applied to wastewater treatment, soil remediation, biodegradable harmful substances, and production of high value-added products. In order to explore basic theory and further applications, we summarize here recent progresses in artificial co-culture systems of using photosynthetic microorganisms, to provide a current scientific understanding for the rational design of the co-culture system based on photosynthetic microorganisms using synthetic biology.
Keywords:photosynthetic microorganisms  co-culture systems  environmental engineering  cell factory  interaction
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