| 特异的中草药配糖体苷酶微生物及其发酵与酶学特性 |
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| 引用本文： | 金凤燮,庄子瑜,鱼红闪,徐金丽,柳青梅,安东善,林完泽,李承宅.特异的中草药配糖体苷酶微生物及其发酵与酶学特性[J].生物工程学报,2009,25(12):1863-1870. |
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| 作者姓名： | 金凤燮 庄子瑜 鱼红闪 徐金丽 柳青梅 安东善 林完泽 李承宅 |
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| 作者单位： | 1. 大连工业大学生物与食品工程学院,大连,116034
2. Environmental and Molecular Microbiology Laboratory, Korea Advanced Institute of Science and Technology, Daejeon 305-701, South Korea |
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| 基金项目： | 国家自然科学基金(Nos.2007600,30371744,30470055);;辽宁省教育厅创新团队项目(Nos.2007T006,2008T008,2009T007)资助~~ |
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| 摘 要： | 配糖体是中草药主要有效成分之一。但是中草药成分并不是活性最佳结构,中草药口服后其成分在消化系统酶和微生物的作用下,转化为另一种结构吸收、起药效;但是体内的这种转化甚微,往往受到人的个体条件的影响。如果这种体内的转化反应在体外实现,中草药成分酶转化为高活性成分,将对创新药、中医药、公众营养食品和保健食品、功能化妆品等意义很大。为此,以下主要介绍本实验室研究过的中草药配糖体苷酶新微生物筛选、分类鉴定,特异的中草药配糖体苷酶的发酵产酶和其酶学特性。
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| 关 键 词： | 中草药配糖体苷酶 新微生物筛选 特异酶发酵 皂苷糖苷酶 |
| 收稿时间： | 2009/9/25 0:00:00 |
Microorganisms of special herb-glycosidases and their fermentation, enzyme properties |
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| Fengxie Jin,Ziyu Zhuang,Hongshan Yu,Jinli Xu,Qingmei Liu,Dongshan An,Wanteak Im and Sungtaik Lee.Microorganisms of special herb-glycosidases and their fermentation, enzyme properties[J].Chinese Journal of Biotechnology,2009,25(12):1863-1870. |
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| Authors: | Fengxie Jin Ziyu Zhuang Hongshan Yu Jinli Xu Qingmei Liu Dongshan An Wanteak Im and Sungtaik Lee |
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| Institution: | College of Bio & Food Technology, Dalian Polytechnic University, Dalian 116034, China;College of Bio & Food Technology, Dalian Polytechnic University, Dalian 116034, China;College of Bio & Food Technology, Dalian Polytechnic University, Dalian 116034, China;College of Bio & Food Technology, Dalian Polytechnic University, Dalian 116034, China;Environmental and Molecular Microbiology Laboratory, Korea Advanced Institute of Science and Technology, Daejeon 305-701, South Korea;Environmental and Molecular Microbiology Laboratory, Korea Advanced Institute of Science and Technology, Daejeon 305-701, South Korea;Environmental and Molecular Microbiology Laboratory, Korea Advanced Institute of Science and Technology, Daejeon 305-701, South Korea;Environmental and Molecular Microbiology Laboratory, Korea Advanced Institute of Science and Technology, Daejeon 305-701, South Korea |
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| Abstract: | Herb-glycosides are main active elements of Zhongcaoyao (Chinese traditional medicines,Chinese medical herbs).However,the herb-glycoside structures are not optimal active structure for the human bodies.After orally taken up,the herb-glycosides of Zhongcaoyao could be changed into other more active structures by the digestive system such as enzymes and intestinal microorganisms;then degraded and absorbed in the human body and play the real role of pharmic effect;but only a small amount could be changed and c... |
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| Keywords: | herb-glycosidases new strain special enzyme fermentation saponin-glycosidases |
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