| 微生物木糖发酵产乙醇的代谢工程 |
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| 引用本文： | 张颖,马瑞强,洪浩舟,张维,陈明,陆伟.微生物木糖发酵产乙醇的代谢工程[J].生物工程学报,2010,26(10):1436-1443. |
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| 作者姓名： | 张颖 马瑞强 洪浩舟 张维 陈明 陆伟 |
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| 作者单位： | 1. 中国农业科学院生物技术研究所,北京,100081
2. 中国农业科学院生物技术研究所,北京100081;中国农业大学生物学院,北京100193 |
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| 基金项目： | 国家重点基础研究发展计划 (973计划) (No. 2007CB707805)，国家高技术研究发展计划 (863计划) (Nos. 2006AA02Z229, 2006AA010101) 资助。 |
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| 摘 要： | 利用木质纤维素发酵生产乙醇具有广泛的应用前景。而自然界中缺少有效转化木糖为乙醇的微生物是充分利用纤维素水解产物、提高乙醇产率、降低生产成本的关键因素。多年来研究者利用分子生物学技术对微生物菌株进行了代谢工程改造,使其能更有效地利用木糖生产乙醇。以下主要对运动发酵单胞菌、大肠杆菌和酵母等候选产乙醇微生物的木糖代谢工程研究进展进行了概述。
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| 关 键 词： | 微生物，木糖，乙醇，代谢工程 |
| 收稿时间： | 2010/5/31 0:00:00 |
Metabolic engineering for microbial production of ethanol from xylose: a review |
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| Ying Zhang,Ruiqiang M,Haozhou Hong,Wei Zhang,Ming Chen and Wei Lu.Metabolic engineering for microbial production of ethanol from xylose: a review[J].Chinese Journal of Biotechnology,2010,26(10):1436-1443. |
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| Authors: | Ying Zhang Ruiqiang M Haozhou Hong Wei Zhang Ming Chen and Wei Lu |
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| Institution: | Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China;Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China; College of Biological Sciences, China Agricultural University, Beijing 100193, China;Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China;Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China;Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China;Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China |
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| Abstract: | Efficient bioconversion of cellulosic biomass and its hydrolysis provide a huge potential in fuel ethanol production. The lack of industrially suitable microorganisms for converting xylose from cellulosic biomass into fuel ethanol has been cited as a major technical bottleneck in the development of a bioethanol industry. In the past decades, many improvements have been made in the metabolic engineering of microorganisms, including Zymomonas mobilis, Escherichia coli, and yeasts, for the fermentation of xylose to produce ethanol by introducing either xylose metabolic genes or ethanol production genes. The history and the current progress in constructing these strains for the efficient fermentation of xylose to ethanol are presented in this review. |
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| Keywords: | microorganisms xylose ethanol metabolic engineering |
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