| 基因编辑技术研究进展及其在苜蓿等豆科饲草作物中的应用 |
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| 引用本文： | 刘欢,孟颖颖,牛丽芳,林浩.基因编辑技术研究进展及其在苜蓿等豆科饲草作物中的应用[J].生物工程学报,2017,33(10):1733-1743. |
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| 作者姓名： | 刘欢 孟颖颖 牛丽芳 林浩 |
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| 作者单位： | 中国农业科学院生物技术研究所，北京 100081,中国农业科学院生物技术研究所，北京 100081,中国农业科学院生物技术研究所，北京 100081,中国农业科学院生物技术研究所，北京 100081 |
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| 基金项目： | 国家自然科学基金 (No. 31570309)，中国农业科学院科技创新工程 (No.Y2016JC30) 资助。 |
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| 摘 要： | 基因编辑是对生物基因组进行靶向修饰的一项新型生物技术,可以在不同物种中实现对目标基因的定点敲除、基因片段置换以及基因定点插入等基因定向编辑,目前基因编辑技术已在植物基因功能解析和作物遗传改良研究中得到广泛应用。本文简要回顾基因编辑技术的发展历程,重点介绍新近发展的CRISPR/Cas9技术在植物中的研究进展,并对CRISPR/Cas基因编辑技术在苜蓿等饲草作物中的应用进行探讨和展望。
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| 关 键 词： | 基因编辑，CRISPR/Cas9，豆科饲草作物，苜蓿 |
| 收稿时间： | 2017/4/24 0:00:00 |
Genome editing technology and its application in forage legumes |
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| Huan Liu,Yingying Meng,Lifang Niu and Hao Lin.Genome editing technology and its application in forage legumes[J].Chinese Journal of Biotechnology,2017,33(10):1733-1743. |
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| Authors: | Huan Liu Yingying Meng Lifang Niu and Hao Lin |
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| Institution: | Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China,Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China,Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China and Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China |
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| Abstract: | Genome editing is a novel targeted genome modification biotechnology, which could successfully mutate specific loci as well as generate gene replacement and insertion in various organisms. So far, genome editing technology has been widely applied in investigating gene function and developing valuable traits in both model plants and major crops. In this review, we briefly survey the historical development of genome editing technology, summarize recent progress using the CRISPR/Cas9 system for plant genome editing and explore the potential of the CRISPR/Cas technology in improving forage legumes. |
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| Keywords: | genome editing CRISPR/Cas9 forage legumes Medicago |
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