蛋白质组学进展

在蛋白质水平上定量、动态、整体性研究生物体的蛋白质组学 ,将在后基因组时代大大增进我们对基因功能的理解。简要介绍了蛋白质组学的概念、研究手段 ,及最新进展

Progress in Proteomics

Proteomics, the large\|scale analysis of proteins, will contribute greatly to our understanding of gene function in the post\|genome era. Proteomics uses a combination of sophisticated techniques including two\|dimensional(2D) gel electrophoresis, mass spectrometry, yeast two\|hybrid system, bioinformatics, etc. to characterize, to quantify, and to analyze cellular proteins in a global way. The application of proteomics provides major opportunities to elucidate disease mechanisms and to identify new therapeutic targets.This review aims to explain the definition of proteomics and then to outline proteomic techniques. Finally, applications to the study of human disease are briefly discussed.