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Immobilization of glycolysis system of yeasts and production of cytidine diphosphate choline |
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| Authors: | Akira Kimura Yoshinori Tatsutomi Naoki Mizushima Atsuo Tanaka Ryu'ichi Matsuno Hirosuke Fukuda |
| Institution: | (1) The Research Institute for Food Science, Kyoto University, 611 Uji, Kyoto, Japan;(2) Department of Food Science and Technology, Faculty of Agriculture, Kyoto University, 606 Kyoto, Japan;(3) Department of Industrial Chemistry, Faculty of Engineering, Kyoto University, 606 Kyoto, Japan |
| Abstract: | Summary Glycolysis system of yeast was successfully immobilized into a derivative of polyethylene glycol hydroxyethylacrylate. The immobilized system could produce ATP and then phosphorylate nucleotides (CMP). The CTP thus formed was effectively converted to CDP-choline in the same system (Fig.2).This system is a kind of bioreactor, consisting of energy (ATP) generating and transformation systems of various substances. |
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