LC-PUFA from photosynthetic microalgae: occurrence, biosynthesis, and prospects in biotechnology |
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Authors: | Khozin-Goldberg Inna Iskandarov Umidjon Cohen Zvi |
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Institution: | 1. The French Associates Institute for Dryland Agriculture and Biotechnologies, The Jacob Blaustein Institutes for Desert Research, Ben-Gurion University of the Negev, Midreshet Ben-Gurion, 84990, Israel 2. Department of Biochemistry and Center for Plant Science Innovation, University of Nebraska, Lincoln, NE, 68503, USA
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Abstract: | Microalgae offer potential for numerous commercial applications, among them the production of long-chain polyunsaturated fatty acids (LC-PUFAs). These valuable fatty acids are important for a variety of nutraceutical and pharmaceutical purposes, and the market for these products is continually growing. An appropriate ratio of LC-PUFA of the ω-3 and ω-6 groups is vital for "healthy" nutrition, and adequate dietary intake has strong health benefits in humans. Microalgae of diverse classes are primary natural producers of LC-PUFA. This mini-review presents an introductory overview of LC-PUFA-related health benefits in humans, describes LC-PUFA occurrence in diverse microalgal classes, depicts the major pathways of their biosynthesis in microalgae, and discusses the prospects for microalgal LC-PUFA production. |
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