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益生菌促进胃肠道健康的机制及应用
引用本文:段云峰,蔡峰,律娜,朱宝利.益生菌促进胃肠道健康的机制及应用[J].微生物学报,2022,62(3):836-847.
作者姓名:段云峰  蔡峰  律娜  朱宝利
作者单位:中国科学院微生物研究所, 病原微生物与免疫学重点实验室, 北京 100101
基金项目:国家重点研发计划重点专项(2018YFC1603903,2018YFC2000505);国家自然科学基金(32170068);济南微生态生物医学省实验室科研项目(JNL-2022013B)
摘    要:人体胃肠道内生活着大量微生物,它们影响着宿主的健康。益生菌是一种活的微生物,对维持肠黏膜屏障功能、调节免疫功能和促进营养物质的代谢吸收等具有重要作用;对肠道菌群紊乱、功能性消化不良、肠胃炎、腹泻、便秘、肠绞痛、肠易激综合征、炎症性肠病以及幽门螺杆菌感染等胃肠道疾病具有良好的应用。本文对益生菌与胃肠道健康的影响作简要概述,为普通消费者和专业人士了解和使用益生菌及其在日常胃肠道健康方面的作用提供支持。

关 键 词:益生菌  乳酸杆菌  双歧杆菌  胃肠道  肠胃炎  幽门螺杆菌
收稿时间:2021/9/15 0:00:00
修稿时间:2021/11/12 0:00:00

The mechanism and application of probiotics in promoting gastrointestinal health
DUAN Yunfeng,CAI Feng,LYU N,ZHU Baoli.The mechanism and application of probiotics in promoting gastrointestinal health[J].Acta Microbiologica Sinica,2022,62(3):836-847.
Authors:DUAN Yunfeng  CAI Feng  LYU N  ZHU Baoli
Institution:Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China
Abstract:The human gastrointestinal tract harbors trillions of microorganisms which affect the host health. Probiotics, as a group of live microorganisms, play a role in maintaining the gut mucosal barrier function, regulating immune function, and promoting the metabolism and absorption of nutrients. Probiotics have demonstrated good performance in the treatment of gut microbiome disorders and gastrointestinal diseases such as functional dyspepsia, gastroenteritis, diarrhea, constipation, colic, irritable bowel syndrome, inflammatory bowel disease, and Helicobacter pylori infection. This article briefly overviewed the effects of probiotics on gastrointestinal health, aiming to provide support for consumers and professionals to understand their role in gastrointestinal health and use probiotics in daily health management.
Keywords:probiotics  Lactobacillus  Bifidobacterium  gastrointestinal tract  gastroenteritis  Helicobacter pylori
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