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戊型肝炎病毒与HBV重叠感染患者的血清学分析
引用本文:徐鸿绪,周淑红,黄健宇,郑晓和,赖在真.戊型肝炎病毒与HBV重叠感染患者的血清学分析[J].中国微生态学杂志,2011,23(6):536-537,542.
作者姓名:徐鸿绪  周淑红  黄健宇  郑晓和  赖在真
作者单位:1. 中山大学附属第一医院,检验医学部,广东,广州,510080
2. 中山大学附属第一医院,东山院区检验科,广东,广州,510080
基金项目:广东省社会发展科技计划资助项目(2010B080701041)
摘    要:目的了解戊型肝炎病毒(HEV)感染情况以及乙型肝炎病毒(HBV)重叠感染戊型肝炎病毒的血清学特点及临床意义。方法对HEV、HBV感染以及HBV重叠HEV感染进行血清学检测并进行统计学分析。结果 HBV重叠感染HEV病例多分布青壮年,且女性多于男性;重叠感染患者的年龄高峰都在21~40岁;HEV感染组与HBV-HEV重叠感染组比较,ALP、TB IL存在明显差异,胆汁淤积增多,黄疸程度加深,肝细胞损伤明显。结论 HEV主要侵犯青壮年,HBV重叠HEV感染后肝细胞损害加重,病情趋向重症化。

关 键 词:戊型肝炎病毒  乙型肝炎病毒  重叠感染  血清学指标

Serological characteristics of Hepatitis B virus superinfection with Hepatitis E virus
XU Hong-xu,ZHOU Shu-hong,HUANG Jian-yu,ZHENG Xiao-he,LAI Zai-zhen.Serological characteristics of Hepatitis B virus superinfection with Hepatitis E virus[J].Chinese Journal of Microecology,2011,23(6):536-537,542.
Authors:XU Hong-xu  ZHOU Shu-hong  HUANG Jian-yu  ZHENG Xiao-he  LAI Zai-zhen
Institution:XU Hong-xu1,ZHOU Shu-hong2,HUANG Jian-yu2,ZHENG Xiao-he2,LAI Zai-zhen2(1.Department of Laboratory Medicine,The First Affiliated Hospital of Sun Yat-sen University,Guangzhou 510080,China,2.Department of Clinical Laboratory,Dongshan Division First Affiliated Hospital of Sun Yat-sen University,China)
Abstract:Objective To explore the serological characteristics and clinical features of Hepatitis E virus(HEV) and Hepatitis B virus(HBV) superinfection with HEV.Method Compared the clinical characteristics of HEV single infection and HBV superinfection with HEV.Result The HEV infection cases were most common in the group of 21 to 40 year-olds with more females than males.The peak age of elderly group were 21 to 40 years old.There were significant differences between HEV and HEV-HBV group with respect of ALP and TBIL...
Keywords:Hepatitis E Virus  Hepatitis B Virus  Superinfection  Serological characteristics  
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