| 模拟失重对大鼠肠道菌群影响的研究 |
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| 引用本文： | 白树民,黄纪明,朱德兵,李志霞,洪建武,周熙成,梁明,熊德鑫.模拟失重对大鼠肠道菌群影响的研究[J].中国微生态学杂志,2001,13(6):326-327. |
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| 作者姓名： | 白树民 黄纪明 朱德兵 李志霞 洪建武 周熙成 梁明 熊德鑫 |
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| 作者单位： | 1. 航天医学工程研究所,北京,100094
2. 解放军第三0四医院创伤中心,北京,100037 |
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| 摘 要： | 目的：研究模拟失重条件下大鼠肠道菌群变化情况。方法：选择性培养基分别对肠球菌、肠杆菌、类杆菌、乳杆菌以及双歧杆菌进行定量测定，扫描电镜观察大鼠盲肠上皮细胞的组织变化。结果：过路菌群中肠杆菌和肠球菌数量增加显著；原籍菌群中双歧杆菌减少十分明显，乳杆菌的数量也有不同程度的减少，而类杆菌的数量有增加的趋势。SD大鼠盲肠出现了肿胀细胞，上皮细胞颈毛排列紊乱、稀疏。结论：模拟失重条件下大鼠肠道微生态出现平衡失调。
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| 关 键 词： | 模拟失重 微生态失调 肠道菌群 大鼠 航天 |
| 文章编号： | 1005-376X(2001)06-0326-02 |
| 修稿时间： | 2001年7月19日 |
STUDY ON THE EFFECT OF MICROFIORA IN RATS GASTROINTESTINAL UNDER TAIL-SUSPENDED SIMULATING WEIGHTLESSNESS |
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| BAI Shu-min,HUANG Ji-ming,ZHU De-bing,et al..STUDY ON THE EFFECT OF MICROFIORA IN RATS GASTROINTESTINAL UNDER TAIL-SUSPENDED SIMULATING WEIGHTLESSNESS[J].Chinese Journal of Microecology,2001,13(6):326-327. |
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| Authors: | BAI Shu-min HUANG Ji-ming ZHU De-bing |
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| Abstract: | Objectives:To investigate the microflora in rats gastrointestinal under simulated weightlessness.Methods:Selective culture media were used to culture Enterococcus,Enterobacteria,Bacteroid,Lactobacillus and Bifidobacteria respectively,scan electron microscope was used to observe the changes of SD mice's caecum mucosa epithelia .Results:The numbers of Enterococcus and Enterobacteria were increased significantly and Bifidobateria decreased markedly;some tumefaction cell were observed in rat's caecum mucosa epithelia and the epithelia villus of caecum was disturbed.Conclusion:The gut microflora appeared dysbiosis under simulated weightlessness. |
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| Keywords: | Simulated weightlessness Microdysbiosis |
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