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耐氧双歧杆菌抗肿瘤机理的研究
引用本文:史俊华,孙君江.耐氧双歧杆菌抗肿瘤机理的研究[J].中国微生态学杂志,1995,7(3):17-20.
作者姓名:史俊华  孙君江
作者单位:(Shi Junhua,et al.(NanJing Rdilway Medical College,Nanjing 210009
摘    要:本研究应用耐氧双歧杆菌治疗荷H22肿瘤鼻,结果发现该菌可通过激活巨噬细胞活性、增强Th、细胞功能,发挥抗肿瘤效应。

关 键 词:耐氧双歧杆菌  抗肿瘤效应  微生态制剂

STUDY ON ANTITUMOR EFFECT OF OXYGEN-RESISTANT BIFIDOBACTERIUM BIFIDUS
Institution:(Shi Junhua,et al.(NanJing Rdilway Medical College,Nanjing 210009)
Abstract:In this study,a strain of strict anaeroblc bificobcteriumbifidus isolated from a healthy person was first tamed to grow underoxygenresistant condition,Then, oxygen-resistant bifidobacterium wasused to treat mice bearing H22 tumor. The results indicated thatbifidobacterium may play an anti-tumor effect by activating macroph-ages characterized with improved lysozyme activities and enhancing Thelper lymphocytes function marked with a high ratio of L3T4 subsets.
Keywords:oxygen-resistant    bifidobacterium  anti-tumor effect  Tlymphocyte subset
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