重症监护病房鲍曼不动杆菌流行病学监测和分析

目的 监测并分析重症监护病房(Intensive care unite,ICU)鲍曼不动杆菌(Acinetobacter baumannii,Ab)的检出率和耐药率的变化趋势,为临床防治Ab感染提供依据.方法 采用细菌耐药监测软件WHONET 5.4回顾分析收住综合性ICU患者送检的各种标本中Ab检出率和耐药率变化趋势...

Monitoring and analyzing the prevalence of Acinetobacter baumannii strains isolated from intensive care unit

Objective To monitor and analyze the detection rate and the variation in drug resistance of Acinetobacter baumannii（Ab） isolated from Intensive Care Unite（ICU）,and provide the evidence for prevention and control of Ab infection.Method The data of Ab isolated from ICU were analyzed by WHONET 5.4 software.Result Between Jan 2005 and Dec 2009,there were 395 Ab strains isolated from patients in ICU.Ab was one of the most common pathogens,accounting for 15.29%（395/2584） of the total pathogens and 21.29%（395/1855） of the Gram-negative bacteria detected,with the respiratory tract being the major source（81.01%）.The antimicrobial resistance rates of Ab were very high,with the resistance rates to carbapenemas and cefoperazone/sulbactam significantly increased from 2009 to 2005（P0.01）.All resistance rates were more than 40.0% in 2009.Conclusion Ab is one of the most important microbials detected in ICU.Its resistance rates are high to all antimicrobials,with the resistance rates to carbapenemas and cefoperazone/sulbactam rising significantly,to which a great attention should be paid.