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香菇C_(91-3)菌发酵液小鼠体内外抗肿瘤作用的研究
引用本文:黄敏,宁安红,张卓然,吴天靖,李岩.香菇C_(91-3)菌发酵液小鼠体内外抗肿瘤作用的研究[J].中国微生态学杂志,1996(3).
作者姓名:黄敏  宁安红  张卓然  吴天靖  李岩
作者单位:大连医科大学微生物学教研室
摘    要:香菇C_(91-3)菌是我们多年筛选出的一株经生物发酵后,其发酵液具有明显的抗肿瘤、抗细菌作用的真菌。研究结果表明:该发酵液具有明显体外抗肿瘤作用的活性物质。对MH_(134)、X5553、Ca761/L、YAC-1、H_(22)、K562抑瘤率为76.7~100%。在体内抗肿瘤实验中,采用H_(22)、S180腹水瘤的研究中,小鼠存活率分别为40%、45%。本文还对香菇C_(91-3)菌发酵液抗肿瘤的机理进行了探讨。

关 键 词:香菇C_(91-3)菌发酵液  抗肿瘤

STUDIES ON ANTITUMOR EFFECTS OF EXTRACT FROM C_(91-3) LENTINUSFERMENTATIVE LIQUID
Huang Min,et al..STUDIES ON ANTITUMOR EFFECTS OF EXTRACT FROM C_(91-3) LENTINUSFERMENTATIVE LIQUID[J].Chinese Journal of Microecology,1996(3).
Authors:Huang Min  
Abstract:Present report concerns the studies on the treatment of H22 and S_(180)ascitic tumor in mice with extract of C_(91-3) lentinus fermentative liquid.In H_(22)ascitic tumor experimental group,the survival rate was 40%and the death date was prolonged 13.6 days than the control group averagely. In S_(180) ascitic tumor experimental group,the survival rate was 45%and the death date was prolonged 14.1 days than the control group.In vitro,the exteact of lentinus fermentative liquid could directlv kill MH_(134),X_(5563),Ca_(761)/L,YAC-1,H_(22),k_(562) cells.
Keywords:Extract of C_(91-3) lentinus fermentative liquid Antitumor  
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