新生儿肠道双歧杆菌数量影响因素与其婴儿期腹泻关系

目的探讨新生儿肠道双歧杆菌数量的相关影响因素,并明确它们与婴儿期腹泻的关系。方法以120例新生儿为研究对象,生后5-7 d均做大便双歧杆菌定量培养,并做相关因素的准确登记,同时严密观察随访至1岁,准确记录其发生腹泻情况。结果母亲分娩方式、临产期及产后是否使用抗生素、母亲妊娠期饮食习惯以及新生儿黄疸期长短与新生儿肠道双歧杆菌数量有相关性。新生儿黄疸期长、母亲临产期及产后使用抗生素均是婴儿腹泻的危险因素;阴道分娩、母亲喜发酵制品及喜素食均是婴儿腹泻的保护因素。结论为避免导致新生儿肠道双歧杆菌数量不足的影响因素,提倡阴道分娩、临产期及产后不用抗生素、妊娠期多食发酵制品和素食,并尽量设法缩短新生儿黄疸时间,以减少婴儿腹泻的发生。

The study on the relationship between the relative factors affecting the Bifidobacterium in neonatal intestines and the infant diarrhea

Objectives To explore the relative factors affecting the Bifidobacterium in neonatal intestines,and identify the relationship between them and the infant diarrhea.Methods The Bifidobacterium from the cultured feces were counted in every neonates.The relationship between the Bifidobacterium in neonatal intestines and its relative factors was analyzed.And their occurrence of diarrhea was followed up for one year.Results The Bifidobacterium in neonatal intestines was related to mode of delivery,maternal administration with antibiotic or not(before and after delivery),dietary habit of the mother,and the duration of neonatal jaundice.The longer duration of neonatal jaundice and maternal administration with antibiotic(before and after delivery) were identified as risk factors.The vaginal delivery and fermented products and vegetable dish to their mothers were identified as protective factors.Conclusions In order to reduce the infant diarrhea,administration with antibiotic to their mothers should be avoided(before and after delivery).Fermented products and vegetable dish,vaginal delivery are encouraged.The duration of neonatal jaundice should be shortened.