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178例小儿肺炎分离菌分布和耐药性分析
引用本文:王峰,张竹馨,王玉屏.178例小儿肺炎分离菌分布和耐药性分析[J].中国微生态学杂志,2005,17(6):458-459.
作者姓名:王峰  张竹馨  王玉屏
作者单位:珠海市妇幼保健院,广东,珠海,519000
摘    要:目的 了解小儿肺炎病原菌谱及耐药性。方法 对2003~2004年178例小儿肺炎的痰标本进行细菌学培养,测定药物敏感性。结果 分离菌中,以革兰阴性菌居首位.占58.51%。肺炎克雷伯菌和大肠埃希菌为主琴芦种,对亚胺培南、美罗培南的耐药性最低;其次为革兰阳性菌,占40.43%,以金黄色葡萄球菌为主,耐甲氧西林的葡萄球菌为57.1%,对万古霉素、替考拉宁最敏感。结论 小儿肺炎病原菌以革兰阴性菌为主,并且出现多重耐药。临床上应避免盲目经验性用药,减少或减缓细菌耐药的发生。

关 键 词:肺炎  小儿  病原菌  耐药性
文章编号:1005-376X(2005)06-0458-02
收稿时间:2005-04-15
修稿时间:2005年4月15日

Distribution and antibiotic resistance of pathogens from 178 cases with pneumonia
WANG Feng,ZHANG Zhu-xin,WANG Yu-ping.Distribution and antibiotic resistance of pathogens from 178 cases with pneumonia[J].Chinese Journal of Microecology,2005,17(6):458-459.
Authors:WANG Feng  ZHANG Zhu-xin  WANG Yu-ping
Institution:Zhuhai Maternity and Child Health Hospital,Zhuhai 519000 ,China
Abstract:Objective To investigate the characteristics of bacterial distribution and drug-resistance among 128 cases with pneumonia in our hospital from July 2003 to.June 2004.Methods Total of 178 cases sputum samples were cultured and isolated.Antibiotic-resistance tests were performed using automated microbial analysis system VITEK-32.Results The main stains were Gram-negative bacilli with the rate of 58.5%.Klebsiella pneumoniae and Escherifia coli were the main stains of them.Their drug-resistance to imipenem was the lowest.The next strains were Gram-positive bacilli with the rate of 40.4%.Staphylococcus was the main one in the isolated Gram-positive bacilli.The isolation rate of MRSA was 57.1%.Vancomycin was the most sensitive for Gram-positive bacilli.Conclusion The major causeof pneumonia might be Gram-egative bacteria with multidrug-resistance.In order to reduce theproduction of drug-resistance,antibiotics shouldn't be used by experience.
Keywords:Pneumonia  child  Bacterial distribution  Drug-resistance
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