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| 中药透皮吸收抗菌活性的测试及对实验动物口腔菌群的影响 | |
| 引用本文： | 李海权,姜欣,韩晓伟,孙宏伟,马贤德,姜伟,孙涛,马国珍.中药透皮吸收抗菌活性的测试及对实验动物口腔菌群的影响[J].中国微生态学杂志,2006,18(1):41-42. |
| 作者姓名： | 李海权 姜欣 韩晓伟 孙宏伟 马贤德 姜伟 孙涛 马国珍 |
| 作者单位： | 1. 辽宁中医学院,辽宁,沈阳,110032 2. 辽宁省肿瘤医院,辽宁,沈阳,110044 3. 沈阳市第四人民医院 |
| 摘 要： | 通过对黄连解毒透皮吸收剂经豚鼠背部透皮吸收后的血清药物浓度测定、体外抗菌活性测定、动物口腔菌群变化结果研究其抗感染的生物学效应及对正常菌群的影响。结果表明受试动物血清中可检测到有效成分并显示出抗菌活性，同时可引起口腔细菌菌群的变化。 |
| 关 键 词： | 透皮吸收 抗菌活性 黄连解毒汤 正常菌群 |
| 文章编号： | 1005-376X（2006）01-0041-02 |
| 收稿时间： | 2005-08-22 |
| 修稿时间： | 2005年8月22日 |
Testing the antibacterial activities and studying the effect to the bacterial colonies in cavies' oral cavity by Chinese traditional medicine absorbed through skin |
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| lI Hai-quan,JIANG Xin,HAN Xiao-wei,et al..Testing the antibacterial activities and studying the effect to the bacterial colonies in cavies'''' oral cavity by Chinese traditional medicine absorbed through skin[J].Chinese Journal of Microecology,2006,18(1):41-42. | |
| Authors: | lI Hai-quan JIANG Xin HAN Xiao-wei |
| Institution: | Liaoning Tradication Chinese Medical College, Shengyang 110032, China |
| Abstract: | To study the biologic effect of anti-infection of huanglian-detoxification decoction absorbed through skin on the cavies' back,and the effect to the bacterial colonies in cavies' oral cavity;the concentration of the medicine in cavies' serum,the antibacterial activities,and the variation of the bacterial colonies in cavies' oral cavity were measured.It could be drew the conclusion that the active components could be examined in the serum,and those components could show the antibacterial activities,at the same time which could caused the variation of the bacterial colonies in cavies' oral cavity. |
| Keywords: | Absorbed through skin Antibacterial activities Huanglian-detoxification Normal flora |
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