| 青春双歧杆菌DM8504菌株对荷瘤小鼠体内NO诱生作用的研究 |
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| 引用本文： | 赛红,康白,陈勇.青春双歧杆菌DM8504菌株对荷瘤小鼠体内NO诱生作用的研究[J].中国微生态学杂志,1999,11(2):70-72. |
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| 作者姓名： | 赛红 康白 陈勇 |
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| 作者单位： | 大连医科大学，抚顺市第二人民医院药剂科 |
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| 摘 要： | 应用处死的青春双歧杆菌ＤＭ８５０４菌株皮下免疫荷瘤小鼠，按Ｇｒｉｅｓ反应原理测定一氧化氮（ＮＯ）的含量。结果表明，双歧杆菌能提高荷瘤小鼠体内ＮＯ的含量，较对照组显著升高，肿瘤组织的坏死程度在处理组与对照组之间也具有显著性差异。提示：在双歧杆菌抗肿瘤作用中，除ＴＮＦ—α外，ＮＯ也发挥重要作用。
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| 关 键 词： | 青春双歧杆菌 一氧化氮 抗肿瘤作用 |
| 修稿时间： | 1998-05-22 |
STUDY OF
BIFIDOBACTERIUM ADOLESCENTIS DM8504 STRAIN ON
NITRIC OXIDE (NO) PRODUCTION IN TUMOR-BEARING MICE |
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| Sai Hong,Kang Bai,et al..STUDY OF
BIFIDOBACTERIUM ADOLESCENTIS DM8504 STRAIN ON
NITRIC OXIDE (NO) PRODUCTION IN TUMOR-BEARING MICE[J].Chinese Journal of Microecology,1999,11(2):70-72. |
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| Authors: | Sai Hong Kang Bai |
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| Institution: | Sai Hong,Kang Bai,et al. Department of Microecology,Dalian Medical Unioersity,Dalian 116027 |
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| Abstract: | In this study,heat-killed cells of Bifidobacterium adolescentis DM8504 strain was injected subcutaneously in HCa-F 25 /16A 3-F tamor-bearing BALB/C mice The level of production of nitric odide (NO) was determined by Griess reaction The result indicated that NO production and extent of tumor necrosis were augmented in tumor-bearing mice treated with B adolescentis Dm8504 strain compared with control group It was suggested that NO could play an important role except TNF-2 in antitumor activity of B adolescentis Dm8504 strain |
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| Keywords: | Bifidobacterium\ adolescentis\ Nitric\ oside\ Antitumor\ actioity |
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