多发性骨髓瘤患者医院感染临床分析

目的 探讨多发性骨髓瘤患者医院感染的临床状况和危险因素。方法 对1994年1月～2001年12月收治的62例多发性骨髓瘤患者医院感染发生情况进行调查分析。结果 多发性骨髓瘤患者发生医院感染33例。感染发生率为53．2％，好发部位为呼吸道、口腔、胃肠道和泌尿道等。结论 多发性骨髓瘤患者医院感染的发生与骨髓瘤细胞含量、疾病Ⅲ期、骨损害、白细胞减少、化疗及住院日等因素有关。应采取相应措施，避免医院感染发生。

A clinical analysis of nosocomial infection in multiple myeloma

Objective To investigate clinic status and risk factors of nosocomial infection in multiple myeloma(MM). Methods WTBZ]Retrospectively studied 62 patients with MM from January 1994 to December 2001. Results It was found 33 cases of the nosocomial infection cases with MM(53.2%). The respiratory tract was the most frequent infection site followed by oral cavity, gastrointestinal tract and urinary tract. Conclusions Nosocomial infection rate of MM was related to the content of myeloma cell, clinical stages, lesion of bone, leukopenia, chemotherapy and hospitalization days. It was feasible to prevent nosocomial infection by controlling the above-mentioned risk factors.