| 灭活双歧杆菌调整小鼠抗生素相关性菌群失调 |
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| 引用本文： | 伦永志,黄敏,袁杰利,康白.灭活双歧杆菌调整小鼠抗生素相关性菌群失调[J].中国微生态学杂志,2002,14(1):8-9. |
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| 作者姓名： | 伦永志 黄敏 袁杰利 康白 |
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| 作者单位： | 1. 大连大学医学院,辽宁,大连,116622
2. 大连医科大学微生态学研究所,辽宁,大连,116027 |
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| 摘 要： | 目的：观察灭活的双歧杆菌及其耗尽培养上清液（SCS）对小鼠肠道生理菌群的影响。方法：应用腹腔注射青霉素造成肠菌群失调动物模型，分别以灭活的双歧杆菌菌液，耗尽培养上清液以及活菌菌液对菌群失调小鼠进行灌胃治疗。结果：活菌组、死菌组及SCS组同自然恢复组的肠道生理菌群相比差异均有显著性，死菌组与SCS组相比，差异也有显著性。结论：灭活的双歧杆菌及其SCS对小鼠肠道菌群失调的恢复具有调整作用，尤其对双歧杆菌和乳酸杆菌有更明显的扶持作用。
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| 关 键 词： | 灭活双歧杆菌 抗生素相关性菌群失调 肠道菌群 调整作用 |
| 文章编号： | 1005-376X(2002)01-0008-02 |
| 修稿时间： | 2001年8月31日 |
MODULATION OF HEAT-KILLED BIFIDOBACTERIUM ON MICROFLORA OF MICE WITH ANTIBIOTIC ASSOCIATION DYSBACTERIOSIS |
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| LUN Yong-zhi,HUANG Min,Yuan Jie-li,KANG Bai.MODULATION OF HEAT-KILLED BIFIDOBACTERIUM ON MICROFLORA OF MICE WITH ANTIBIOTIC ASSOCIATION DYSBACTERIOSIS[J].Chinese Journal of Microecology,2002,14(1):8-9. |
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| Authors: | LUN Yong-zhi HUANG Min Yuan Jie-li KANG Bai |
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| Abstract: | Objective:To evaluate heat-killed Bifidobacterium and its spent culture supernatant(scs) of having effect on microflora of mice with antibiotic association dysbacteriosis Methods: Made animal's model of dysbcteriosis by means of penicillin injection to mice ip,then experimental treatment was made PO for variaus group treated group Results: There is significant difference between the normal group and the Bifidobacterium group,the heat-killed Bifidobacterium group and the spent cuture supernatant group We compared the heat-killed Bifidobacterium group and its spent culture supernatant group,we draw an conclusion that there isn't obvious difference Conclusions: Heat-killed Bifidobacteriumand and SCS have effect on microflora of mice,which may regulate the normal intestinal flora of mice They are more obviously helpful to raising Bifidobacteriam and Lactobacillus |
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| Keywords: | Bifidobacterium Dybacteriosis Microflora |
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