子宫托对阴道微生态的影响以及应用雌激素的作用

通常将阴道前后壁、膀胱或直肠等盆腔脏器突入阴道内,称为盆腔脏器脱垂,常发生于老年女性。盆腔脏器脱垂及其引起的排尿相关症状严重影响患者的生活质量。目前临床上治疗盆腔脏器脱垂最常用的方法为佩戴子宫托。子宫托治疗盆腔脏器脱垂已有久远的历史。使用子宫托可明显改善盆腔脏器脱垂患者的临床症状,提高患者的生活质量。然而研究显示,对于机体而言,阴道内放置子宫托可在一定程度上影响阴道微生态环境平衡,从而使佩戴子宫托患者的细菌性阴道病患病率增加4.37倍。同时使用雌激素可明显减少由使用子宫托引起的阴道微环境改变、出血、溃疡等症状的发生。现就子宫托对阴道微生态的影响以及应用雌激素的作用做一简要综述。

The influence of pessary on vaginal microecology and the role of estrogens

Abstract: Usually, a condition in which pelvic organs such as the anterior and posterior wall of the vagina, bladder or rectum thrust into the vagina, is called pelvic organ prolapse. It often occurs in elderly women. Pelvic organ prolapse and the resulted urination-associated symptoms seriously affect the quality of life of the patients. At present, the most common way to treat pelvic organ prolapse is to insert pessary. The treatment of pelvic organ prolapsed with pessary has a long history. While the use of pessary can significantly relieve the clinical symptoms and improve the quality of life of the patients, research showed that it can also influence the balance of vaginal microecological environment to a certain extent, resulting in a 4.37-fold increased prevalence rate of bacterial vaginal diseases. Concurrent use of estrogens can significantly reduce the occurrences of vaginal microenvironment change, bleeding, ulcers and other symptoms. This article reviews the influence of pessary on vaginal microecology and the role of estrogens.