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布拉酵母菌在成人感染性腹泻治疗中的作用研究
引用本文:汪鑫,叶程军,余红军,张福生,冷莉莉.布拉酵母菌在成人感染性腹泻治疗中的作用研究[J].中国微生态学杂志,2013(10):1179-1180,1187.
作者姓名:汪鑫  叶程军  余红军  张福生  冷莉莉
作者单位:浙江省龙游县人民医院感染科,浙江衢州324400
摘    要:目的评价布拉酵母菌在感染性腹泻治疗中的作用及影响因素。方法收集浙江省龙游县人民医院自2010年5月至2012年10月共36例感染性腹泻病例,其中18例患者治疗应用左氧氟沙星联合布拉酵母菌,对照组18例患者单用左氧氟沙星,观察患者症状的改善状况和治愈疗程的差异。结果左氧氟沙星联合布拉酵母菌治疗患者大便次数在疗程第2~4天较单用左氧氟沙星患者明显缩短,两组比较差异有统计学意义(P 〈 0. 05);联合治疗组平均止泻时间为(3. 85±1. 74) d,单用左氧氟沙星治疗组的平均止泻时间为(4. 89 ± 1. 67)d,两组比较差异有统计学意义〈0. 05)。结论感染性腹泻患者联合应用布拉酵母菌,有助于平衡肠道菌群,及早康复。

关 键 词:感染性腹泻  布拉酵母菌  肠道  左氧氟沙星

Clinical efficacy of Saccharomyces boulardii in adult infectious diarrhea
WANG Xin,YE Chen-jun,YU Hong-jun,ZHANG Fu-sheng,LENG Li-li.Clinical efficacy of Saccharomyces boulardii in adult infectious diarrhea[J].Chinese Journal of Microecology,2013(10):1179-1180,1187.
Authors:WANG Xin  YE Chen-jun  YU Hong-jun  ZHANG Fu-sheng  LENG Li-li
Institution:(Department of Infectious Diseases, Longyou People's Hospital, Quzhou 324400, China)
Abstract:Objective To evaluate the clinical efficacy of Saccharomyces boulardii in adult infectious diarrhea. Methods 36 initial diagnosed cases of infectious diarrhea were enrolled in our present study from May, 2010 to October, 2012. 18 cases were treated withlevofloxacin in combination with Saccharomyces boulardii randomly, while other 18 cases were treated with levofloxacin only. The durationand clinical efficacy were compared between the two groups. Results The duration of diarrhea was shorter in cases that treated with levofloxacin in combination with 5. boulardii in the course of 2 to 4 days (P 〈 0. 05 ). The mean time of recovery was 3. 85 ± 1. 74 days inlevofloxacin in combination with S、boulardii group,while it was 4. 89 ± 1, 67 days in levofloxacin group,which showed significant differ-ent between the two groups ( P 〈 0. 05 ) . Conclusion Patients suffered from infectious diarrhea were easily resolved in combination Saccharomyces boulardii, which might help to restore the gut eubiosis.
Keywords:Infectious diarrhea  Saccharomyces boulardii  Gut  Levofloxacin
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