| 黄瓜香等山野菜对糖尿病大鼠脂质代谢及肠道正常菌群的影响 |
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| 引用本文： | 王海波,侯霞,杨景云,吴庆田.黄瓜香等山野菜对糖尿病大鼠脂质代谢及肠道正常菌群的影响[J].中国微生态学杂志,2009,21(10):916-917. |
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| 作者姓名： | 王海波 侯霞 杨景云 吴庆田 |
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| 作者单位： | 1. 宁安市人民医院,内四科,黑龙江,宁安,157400
2. 佳木斯大学基础医学院,黑龙江,佳木斯,154007 |
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| 摘 要： | 目的观察黄瓜香等对糖尿病大鼠脂质代谢的影响,并进一步探讨其调脂机制。方法选取糖尿病大鼠灌胃给予黄瓜香提取液120mg/（kg.d）,共8周,检测其空腹血脂变化,及其肠道菌群变化。结果（1）经黄瓜香提取物治疗后,治疗组较糖尿病组,甘油三脂、低密度脂蛋白和胆固醇明显降低（P〈0.01）;（2）糖尿病组肠道菌群较正常组有明显变化（P〈0.01）,尤其双歧杆菌、乳杆菌等明显减少,而治疗后肠道菌群得到调整。结论黄瓜香提取物可能通过扶植肠道菌群生长繁殖,对脂质代谢发挥作用,从而达到其调脂目的。
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| 关 键 词： | 黄瓜香 糖尿病 脂质代谢 肠道菌群 |
Role of Huangguaxiang in lipid metabolism and its effect on normal intestinal bacteria of diabetic rats |
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| WANG Hai-bo,HOU Xia,YANG Jing-yun,WU Qing-tian.Role of Huangguaxiang in lipid metabolism and its effect on normal intestinal bacteria of diabetic rats[J].Chinese Journal of Microecology,2009,21(10):916-917. |
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| Authors: | WANG Hai-bo HOU Xia YANG Jing-yun WU Qing-tian |
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| Institution: | WANG Hai-bo , HOU Xia, YANG Jing-yun, WU Qing-tian ( 1. Medical Department of Ning＇an People＇s Hospital, Ning＇an 157400, China ;2. Foundation Medical College of Jiamusi University, Jiamusi 154007, China) |
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| Abstract: | Objective To observe the effects of Huangguaxiang {Matteuccia struthiopteris) on lipid metabolism of diabetic Tats, and research the mechanism of lipid regulation ulteriorly. Method Rats were administered Huangguaxiang extract 120 mg/(kg · d) orally for 8 weeks. He change of blood-fat in limosis condition and intestinal microflora were detected. Result (1) The levels of Triglyceride, low density lipoprotein and cholesterol were lower in treatment group than those in diabetic group (P<0.01). (2) The intestinal microflora were improved in treatment group,compared to the normal group. Conclusion Huangguaxiang could reduce the level of blood-fat through promoting the growth of intestinal flora and improving lipid metabolism. |
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| Keywords: | Huangguaxiang Diabetes Lipid metabolism Intestinal microflora |
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