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自然流产胚胎组织解脲脲原体检测分析
引用本文:林巧爱,周丽萍,陈柏坤,陈向敏,薛向阳,方周溪,王琳,赵宇,泮新花.自然流产胚胎组织解脲脲原体检测分析[J].中国微生态学杂志,2001,13(2):92-93.
作者姓名:林巧爱  周丽萍  陈柏坤  陈向敏  薛向阳  方周溪  王琳  赵宇  泮新花
作者单位:1. 温州医学院微生物学教研室,
2. 温州医学院电镜室,
3. 温州医学院附二院妇产科,
基金项目:浙江省自然基金资助项目(399066)
摘    要:初步探讨解脲脲原体(Uu)感染与自然流产的相关性。对82例自然流产,44例人工流产(对照组)的胚胎组织进行Uu的人工分离培养,并对部分组织的超薄切片及培养物负染片置电镜下观察。结果显示,自然流产胚胎组织Uu的检出率为64.6%(53.82),与对照组相比6.8%(3/44),具有显著性差异(P<0.001);电镜下观察,Uu检出阳性标本中合体滋养细胞和细胞滋养细胞膜表面见大量的Uu颗粒,与阳性培养物经负染后了颗粒相似,而Uu阴性对照标本中未见此颗粒,提示:Uu可引起宫内感染,损伤绒毛膜滋养细胞,是导致自然流产的重要病原体之一。

关 键 词:解脲脲原体  流产  超薄切片  胚胎组织
文章编号:1005-376X(2001)04-0092-02
修稿时间:2000年11月7日

UREAPLASMA UREALYTICUM INFECTION IN SPORTANEOUS ABORTION
LIN Qiao-ai,ZHOU Lip-ping,CHEN Bo-kun,et al..UREAPLASMA UREALYTICUM INFECTION IN SPORTANEOUS ABORTION[J].Chinese Journal of Microecology,2001,13(2):92-93.
Authors:LIN Qiao-ai  ZHOU Lip-ping  CHEN Bo-kun  
Abstract:Ureaplasma urealyticum in aborted tissue were examined in 82 women with spontaneous abortion(test group)and 44 women of induced aborted (control group).The ulrtrathin section were used to detect the aborted tissues with Uu.The results showed that the positive isolation rate of ureaplasma urealyticum was significantly higher in the test group than that in the control group(64.6%VS6.8%).Electron microscopy demontrated that large amount of Uu particles deposited around the membrane of the cytotrophoblasts in the Uu-positive group.In contrast,no Uu particles was seen in Uu-negative samples.From this study we conclude that ureaplasma urealyticum might be a caues of spontaneous abortion.
Keywords:Ureaplasma urealyticum  Abrotion  Electron microscopy  
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