| 阻断白色念珠菌粘附口腔膜上皮细胞的实验研究 |
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| 引用本文： | 刘为国,伦永志,黄敏,徐曼丽.阻断白色念珠菌粘附口腔膜上皮细胞的实验研究[J].中国微生态学杂志,2001,13(3):164-165. |
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| 作者姓名： | 刘为国 伦永志 黄敏 徐曼丽 |
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| 作者单位： | 1. 大连大学医学院,大连医科大学
2. 大连大学医学院,大连医科大学, |
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| 摘 要： | 白色念珠菌的粘附与其表面甘露糖结构有关，为探讨阻断粘附的方法，我们采用体外法测定其对口腔上皮细胞的粘附数量，显示：白色念珠菌粘附感染上皮细胞后，甘露糖可以在一定程度上减少粘附，绿慕安及刀豆素A可以有效地减少粘附。提示甘露糖及绿慕安可能有助于治疗白色念珠菌感染。
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| 关 键 词： | 白色念珠菌 口腔上皮细胞 粘附 |
| 文章编号： | 1005-376X(2001)06-0164-02 |
| 修稿时间： | 2001年2月26日 |
THE EXPERIMENTAL STUDY OF INHIBITING CADIDA AIBI CANSADHERE TO HUMAN EPITHELIUM |
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| LIU Wei guo,LUN Yong zhi,HUANG Min,et al.THE EXPERIMENTAL STUDY OF INHIBITING CADIDA AIBI CANSADHERE TO HUMAN EPITHELIUM[J].Chinese Journal of Microecology,2001,13(3):164-165. |
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| Authors: | LIU Wei guo LUN Yong zhi HUANG Min |
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| Abstract: | Mannose containing moieties on the surface of Cadida albicans could mediate the adherence of this yeasts to human epithelium. To study the methods of inhibiting adherence, we measured the quantity of adherecne of Cadida albicans to epithelial cells in vitro. The results showed that mannose can inhibited adherence partly, and PA MSHA (Pseudomonas aeruginosa with Mannose Sensitive hemagglutination Pili)vaccin and concanavalin A can inhibited adherence effectively after Cadida albicans adhered to epithelial cells. Therefore mannose and PA MSHA vaccin could prevent adhesion and infections. |
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| Keywords: | Cadida albicans human epithelial cells adherence |
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