Bacterial L-arabinose isomerases: industrial application for D-tagatose production |
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Authors: | Boudebbouze Samira Maguin Emmanuelle Rhimi Moez |
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Institution: | Laboratory for Biocrystallography and Structural Biology of Therapeutical Targets, BMSSI- Institut de Biologie et Chimie des Proteines, UMR 5086-CNRS/Universite de Lyon, FR3302 BioSciences Gerland - Lyon Sud, F-69367 Lyon cedex 07, France. |
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Abstract: | D-tagatose is a natural monosaccharide with a low caloric value and has an anti-hyperglycemiant effect. This hexose has potential applications both in pharmaceutical and agro-food industries. However, the use of D-tagatose remains limited by its production cost. Many production procedures including chemical and biological processes were developed and patented. The most profitable production way is based on the use of L-arabinose isomerase which allows the manufacture of D-tagatose with an attractive rate. Future developments are focused on the generation of L-arabinose isomerases having biochemical properties satisfying the industrial applications. This report provides a brief review of the most recent patents that have been published relating to this area. |
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