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High frequency electric fields for trapping of viruses
Authors:Torsten Müller  Stefan Fiedler  Thomas Schnelle  Kai Ludwig  Hartmut Jung  Günter Fuhr
Institution:(1) Humboldt-Universität zu Berlin, Institut für Biol.ogie, Invalidenstr. 42, 10115 Berlin;(2) Lehrstuhl für Membranphysiologie, Germany;(3) Logware GmbH, Schwedenstrabetae 9, 13359 Berlin
Abstract:Summary Combining dielectrophoretic and hydrodynamic forces in micro electrode structures allows enrichment and stable trapping of viruses in aqueous solutions. Fluorescently labelled Influenza and Sendai viruses were collected from solutions of 2*105 – 2*108 viruses/mgrl within a few seconds. In the central part of the trap a virus aggregate of about 2–9 mgrm in diameter was formed. This corresponds to a local enrichment of viruses up to a factor of about 1400.
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