Synthesis and bio-evaluation of aryl hydrazono esters for oviposition responses in Aedes albopictus |
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| Authors: | Bandyopadhyay Prabal Guha Lopamudra Seenivasagan T Sathe Manisha Sharma Pratibha Parashar B D Kaushik M P |
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| Institution: | a Defence R & D Establishment, Jhansi Road, Gwalior 474 002 (M.P.), India
b School of Chemical Sciences, Devi Ahilya University, Khandwa Road, Indore 452 001 (M.P.), India |
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| Abstract: | A novel series of aryl hydrazono esters (AHE) (1-13) were synthesized (yield 76-98%) to study the oviposition responses in Aedes albopictus (Skuse) mosquitoes for the first time. At a concentration of 10 μg ml−1 in dual choice experiment, among the screened compounds, AHE-12 showed remarkable oviposition attractant activity with an oviposition activity index (OAI) of +0.299 (greater than 95% confidence limit) comparable to p-cresol (OAI +0.320) which is well-reported oviposition attractant for Aedes aegypti. Conversely, AHE-10 exhibited highest oviposition deterrent activity with OAI −0.247. The possible utilization of these compounds will be in integrated vector management strategies. |
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| Keywords: | Aryl hydrazono ester Oviposition Aedes albopictus Dengue Chikungunya |
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