Acyl-CoA: cholesterol acyltransferase inhibitory activity of ginseng sapogenins, produced from the ginseng saponins. |
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| Authors: | B M Kwon M K Kim N I Baek D S Kim J D Park Y K Kim H K Lee S I Kim |
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| Institution: | Korea Research Institute of Bioscience and Biotechnology, Yusung, Taejon. |
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| Abstract: | Ginseng sapogenins were produced from ginseng saponins, isolated from Korean ginseng roots. Ginseng saponins very mildly inhibited acyl-CoA:cholesterol acyltransferase (ACAT) in vitro, however, the sapogenins showed strong inhibitory activity on microsomal ACAT. Therefore, the sapogenins will be one of key ingredients of ginseng affected a lowering of the serum total cholesterol level. |
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