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Human Embryonic Stem Cells Do Not Change Their X Inactivation Status during Differentiation
Authors:Sanjeet Patel  Giancarlo Bonora  Anna Sahakyan  Rachel Kim  Constantinos Chronis  Justin Langerman  Sorel Fitz-Gibbon  Liudmilla Rubbi  Rhys JP Skelton  Reza Ardehali  Matteo Pellegrini  William E Lowry  Amander T Clark  Kathrin Plath
Institution:1. Department of Biological Chemistry, Molecular Biology Institute, Jonsson Comprehensive Cancer Center, Bioinformatics Program, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA;2. Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA;3. Division of Cardiology, Department of Internal Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA
Abstract:
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  • Keywords:human induced pluripotent stem cells  human embryonic stem cells  X-inactivation  X-chromosome dosage compensation  Xist  inactive X chromosome  Xi-erosion  DNA methylation
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