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SPHK2-Generated S1P in CD11b+ Macrophages Blocks STING to Suppress the Inflammatory Function of Alveolar Macrophages
Institution:1. Department of Pharmacology and Center for Lung and Vascular Biology, College of Medicine, University of Illinois, Chicago, IL, USA;2. Department of Biochemistry and Molecular Genetics, College of Medicine, University of Illinois, Chicago, IL, USA;3. Department of Medicine, College of Medicine, University of Illinois, Chicago, IL, USA
Abstract:
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  • Keywords:acute lung injury  sting  sphingosine kinase 2  alveolar macrophages  recruited macrophages  CD11b+ macrophages  S1P  inflammation  cGAMP
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