Oxidative stress in Perna perna and other bivalves as indicators of environmental stress in the Brazilian marine environment: antioxidants, lipid peroxidation and DNA damage |
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Authors: | Alves de Almeida Eduardo Celso Dias Bainy Afonso Paula de Melo Loureiro Ana Regina Martinez Glaucia Miyamoto Sayuri Onuki Janice Fujita Barbosa Lívea Carrião Machado Garcia Camila Manso Prado Fernanda Eliza Ronsein Graziella Alexandre Sigolo Carlos Barbosa Brochini Cláudia Maria Gracioso Martins Ana Helena Gennari de Medeiros Marisa Di Mascio Paolo |
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Institution: | 1. Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, CP 26.077, 05513-970, São Paulo, Brazil;2. Departamento de Bioquímica, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, 88040-900, Florianópolis, Brazil;3. Departamento de Análises Clínicas e Toxicológicas, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, 05508-900, São Paulo, Brazil;4. Departamento de Bioquímica e Biologia Molecular, Setor de Ciências Biológicas, Universidade Federal do Paraná, CP 19046, 81531-990, Curitiba-PR, Brazil |
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Abstract: | Oxidative stress can take place in marine bivalves under a series of environmental adverse conditions. The study of different systems related to oxidative stress in these organisms can give important information about their physiological status and also about environmental health. Bivalves have been proposed as good sentinel organisms in pollution monitoring studies through the analysis of biochemical biomarkers, and most of the biomarkers analyzed are those related to oxidative stress. However, it is very important to know how other environmental factors not associated to the presence of pollutants might affect these parameters. We have studied a series of mechanisms related to oxidative stress in mussels which inhabit the Brazilian coast, especially in Perna perna species, subjected to different stress conditions, such as the exposure to different contaminants in the laboratory and in the field, the exposure of mussels to air and re-submersion, simulating the tidal oscillations, and in mussels collected at different seasons. Both oxidative damage levels and antioxidant defense systems were strongly affected by the different environmental stress. This review summarizes the data obtained in some studies carried out in bivalves from the Brazilian coast. |
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