Is G1 normally distributed? |
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Authors: | RT Hersh PA Kitos |
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Institution: | Department of Biochemistry, University of Kansas, Lawrence, Kansas 66045, U.S.A. |
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Abstract: | The normal distribution parameters were calculated for seven sets of cell cycle data of animal cells in culture. These include two sets of intermitotic times (rat S6/1 cells and mouse fibroblast L 929) and five sets of DNA synthesis (two of mouse fibroblast line L 929, two Chinese hamster CHO lines and Syrian hamster line BHK 21/613).It is demonstrated that within the errors involved the experimental data fit the normal distribution adequately. The Smith-Martin model and the normal distribution are briefly discussed in relationship to the initial curvature observed in a semilogarithmic presentation of such data. |
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