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植物NLR免疫受体的识别、免疫激活与信号调控
引用本文:覃磊,彭志红,夏石头.植物NLR免疫受体的识别、免疫激活与信号调控[J].植物学报,2022,57(1):12-23.
作者姓名:覃磊  彭志红  夏石头
作者单位:1湖南农业大学, 植物激素与生长发育湖南省重点实验室, 长沙 4101282湖南农业大学生物科学技术学院, 长沙 410128
基金项目:国家自然科学基金(31971836);湖南省自然科学基金(2019JJ40126)
摘    要:高等植物进化出大量膜表面和胞内免疫受体以感知各种病原信号, 抵御病原物入侵。其中, 细胞表面的模式识别受体感知模式分子后激活基础免疫反应, 核苷酸结合和富亮氨酸重复蛋白(NLRs)则通过感知病原微生物分泌的效应蛋白激活特异免疫反应, 导致超敏反应与细胞死亡。该文主要综述了NLRs对效应蛋白的识别、植物免疫激活及下游信号调控的最新研究进展。

关 键 词:植物免疫  NLRs  受体识别  信号调控  
收稿时间:2021-09-14

Recognition,Immune Activation and Signal Regulation of Plant NLR Immune Receptor
Lei Qin,Zhihong Peng,Shitou Xia.Recognition,Immune Activation and Signal Regulation of Plant NLR Immune Receptor[J].Bulletin of Botany,2022,57(1):12-23.
Authors:Lei Qin  Zhihong Peng  Shitou Xia
Institution:1Hunan Provincial Key Laboratory of Phytohormones and Growth Development, Hunan Agricultural University, Changsha 410128, China2College of Bioscience and Biotechnology, Hunan Agricultural University, Changsha 410128, China
Abstract:A large area of membrane surface and intracellular immune receptors have been evolved in higher plants to sense various pathogen signals and prevent pathogen invasion. Among them, pattern recognition receptors on the cell surface activate basic immune response after sensing pattern molecules, while nucleotide-bounding leucine-rich repeat proteins (NLRs) activate specific immune response by sensing effector proteins secreted by pathogenic microorganisms, resulting in hypersensitivity and cell death. In this review, the latest research progress of plant immunity is mainly reviewed from the aspects of NLRs on the recognition of effector proteins, plant immune activation and downstream signal regulation.
Keywords:plant immunity                                                                                                                        NLRs                                                                                                                        receptor recognition                                                                                                                        signal regulation
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