蛋白质组技术在鼠胚胎早期发育研究中的应用

人类基因组大规模测序,揭示基因组精细结构的同时,还显示出基因数量的有限性和结构的相对稳定。随分析仪器和生物技术的飞速发展,创立了与基因组相对应的蛋白质组学,将精力集中于从生命功能的执行体———蛋白质水平研究基因的表达及功能。生殖技术的研究已取得了惊人的进展,但人们对生殖尤其是人类生殖的分子机制了解仍很贫乏。鼠胚胎发育过程蛋白质组的研究,为了解人类生殖健康和疾病发生的机制提供了有意义的资料 。

Study on the Proteome of Embryo of Early Stage in Mice

With the human genome project fulfilling,it is revealed that human being just possess limited genes and a stable genome. The developments of biotechnology promote the establishment of the proteome which focus on the level of protein expression and function . Recent developments in certain areas of reproductive technology have been remarkable and advances are continuing at a considerable rate. However ,our understanding of the molecular basis of most aspects of reproduction, particularly in the human ,is still extremely poor. Study on the proteome of embryo in mice will contribute largely to the knowledge of mechanism during health and disease of reproduction.;