神经导管研究与进展

随着机械化程度的提高和交通事业的发展，周围神经损伤发生率大幅度的上升。虽然通过手术的方法可以进行端对端的缝合，但是神经恢复的效果仍然不理想，特别是存在神经短距离缺损时，神经导管可为神经的修复提供一个合适的微环境，使得神经纤维能够再生并顺利到达远端。本文介绍了受损神经恢复效果的评价标准，神经导管材料的研究进展，神经生长因子对神经再生的影响因素及作用机理，和神经导管的制备方法，且在总结前人研究的基础上，给出适合于神经导管支架所需的材料和结构要求。

Researches and Developments of Nerve Guide Conduits

As the development of mechanization and transportation,there are more and more peripheral nerve wound happened. Although the damaged nerves can be bridged by an end to end surgery operation, when the damnification is very long, the surgery would loss its effect because of existing of stress between the two ends. Nerve guide conduit can provide a proper micro-environment for the self-regeneration of damaged nerve. The judge criterion of nerve self-regeneration, the development of nerve guide conduits materials, the effect of nerve generated factors, some preparation methods of nerve guide conduits were introduced, and on the base of foregoing researches, present the required properties of materials and structures for appropriate nerve guide conduit.