| 抗菌肽基因工程研究及其表达策略 |
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| 引用本文： | 冯兴军,王建华,单安山.抗菌肽基因工程研究及其表达策略[J].中国生物工程杂志,2006,26(3):63-67. |
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| 作者姓名： | 冯兴军 王建华 单安山 |
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| 作者单位： | 中国农业科学院饲料研究所基因工程研究室 东北农业大学动物营养研究所 |
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| 基金项目： | 国家科技攻关项目;北京市自然科学基金 |
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| 摘 要： | 抗菌肽广泛存在于多种生物体内，具有广谱抗菌、调节免疫、抑制肿瘤等多种生物学功能，作用机制独特，是目前基因工程研究的热点之一。本文综述了抗菌肽的一般性质及其国内外基因工程研究进展，探讨了在抗菌肽转基因研究中采用的表达策略及理论依据。
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| 关 键 词： | 抗菌肽 基因工程 融合表达 |
| 收稿时间： | 2005-09-05 |
| 修稿时间： | 2005年9月6日 |
A REVIEW ON GENE ENGINEERING AND TRANSGENIC EXPRESSION STRATEGY OF ANTIMICROBIAL PEPTIDES |
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| FENG Xing-jun,WANG Jian-hua,SHAN An-shan.A REVIEW ON GENE ENGINEERING AND TRANSGENIC EXPRESSION STRATEGY OF ANTIMICROBIAL PEPTIDES[J].China Biotechnology,2006,26(3):63-67. |
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| Authors: | FENG Xing-jun WANG Jian-hua SHAN An-shan |
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| Abstract: | Antimicrobial peptides distribute in a wide variety of organisms and show the multiple biological functions including broad-spectrum antibacterial, immune- modulating and inhibiting tumor activity, as well as exhibiting unique mechanism, which made antibacterial peptides a research focus in the field of gene engineering. It was reviewed on advances of general properties and gene engineering research of antimicrobial peptides. And their transgenic expression strategy and theoretical foundation were also discussed. |
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| Keywords: | Antimicrobial peptides Gene engineering Fusion expression |
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