| 斑马鱼在抗肿瘤血管生成研究中的应用 |
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| 引用本文： | 邱胜红,黄思超,蔡绍晖.斑马鱼在抗肿瘤血管生成研究中的应用[J].中国生物工程杂志,2009,29(10):98-101. |
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| 作者姓名： | 邱胜红 黄思超 蔡绍晖 |
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| 作者单位： | 暨南大学药学院 广州 510632 |
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| 摘 要： | 近年来，斑马鱼作为一种新的模式生物，在胚胎的分子发育机制、疾病模型的构建以及药物筛选等研究中受到了广泛重视。随着先进的基因诱导技术和共聚焦显微观察技术的发展，斑马鱼已经在抗肿瘤血管生成药物研究中得到广泛应用。就斑马鱼在抗肿瘤血管生成药物筛选及其在肿瘤血管生成机制方面研究的应用作一综述。
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| 关 键 词： | 斑马鱼 抗肿瘤血管生成 药物筛选 |
| 收稿时间： | 2009-06-03 |
| 修稿时间： | 2009-08-12 |
The Application of Zebrafish in the Study of the Tumor Antiangiogenesis |
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| QIU Sheng-hong,HUANG Si-chao,CAI Shao-hui.The Application of Zebrafish in the Study of the Tumor Antiangiogenesis[J].China Biotechnology,2009,29(10):98-101. |
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| Authors: | QIU Sheng-hong HUANG Si-chao CAI Shao-hui |
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| Institution: | College of Pharmacy, Jinan University, Guangzhou 510632, China |
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| Abstract: | Recently, zebrafish，as a new model species,has been used widely in the study of developmental mechanism of the embryo, a model of human disease and the drug screening. Zebrafish has been applied widely in the study of the drug for tumor antiangiogenesis with the development of the advanced technology of the mutagenesis and the confocal microscopy using for observation.Zebrafish applied in the screening of tumor antiangiogenesis drug and the mechanism of tumor angiogenesis are summered. |
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| Keywords: | Zebrafish Tumor Drug screening |
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