| 纳豆激酶溶解血栓机制 |
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| 引用本文： | 陈丽娟,沙长青,任永春,奚新伟,王佳龙.纳豆激酶溶解血栓机制[J].中国生物工程杂志,2003,23(4):53-56. |
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| 作者姓名： | 陈丽娟 沙长青 任永春 奚新伟 王佳龙 |
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| 作者单位： | 黑龙江省科学院应用微生物研究所 哈尔滨 150010 |
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| 摘 要： | 根据已有文献报道,综述了关于纳豆激酶溶栓机制的研究进展,将纳豆激酶的溶栓机制归纳为以下四点:直接溶栓作用;刺激血管内皮细胞产生内源tPA;激活体内尿激酶原转变为尿激酶;通过降解和失活纤溶酶原激活剂的抑制剂(PAI1)调控纤溶作用 。
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| 关 键 词： | 纳豆激酶 纤维蛋白 纤溶酶 PAI-1 |
Advances in Research on Thrombolysis Mechanism of Nattokinase |
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| Cheng Lijuan,Sha Changqing,Ren Yongchun,Xi Xingwei,Wang Jialong.Advances in Research on Thrombolysis Mechanism of Nattokinase[J].China Biotechnology,2003,23(4):53-56. |
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| Authors: | Cheng Lijuan Sha Changqing Ren Yongchun Xi Xingwei Wang Jialong |
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| Institution: | Cheng Lijuan 1 Sha Changqing 1 Ren Yongchun 2 Xi Xingwei 1 Wang Jialong 1 (1 Institute of Applied Microbiology Heilongjiang Academy of Sciences Harbin 150010) (2 Chenlong Pharmaceutical Institute of Harbin Harbin 150072) |
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| Abstract: | The article reviewed the Advances in research of Thrombolysis mechanism of Nattokinase and summarized it as follows:Direct thrombolysis; Endogenous t-PA was produced by Nattokinase stimulating endothelium; Pro-urokinase was activated by nattokinase; Fibrinolysis effect was regulated by digesting and inactivating PAI-1.; |
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| Keywords: | Nattokinase Fibrin Plasmin PAI-1 |
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