| 口服轮状病毒活疫苗的安全性临床观察 |
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| 引用本文： | 沈国红,辛强,于小红,孟璐欣.口服轮状病毒活疫苗的安全性临床观察[J].微生物学免疫学进展,2006,34(3):13-14. |
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| 作者姓名： | 沈国红 辛强 于小红 孟璐欣 |
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| 作者单位： | 1. 济南市中心医院,济南,250013
2. 历下区疾病预防控制中心,济南,250013 |
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| 摘 要： | 为了观察口服轮状病毒活疫苗的安全性,2004年4~10月在济南市中心医院预防接种门诊对总服用该疫苗的410例7月龄~3岁的幼儿密切观察其反应,测量腋下体温并询问有无不适症状等。结果显示,95.61%幼儿(392/410)无不良反应;约4.39%(18/410)出现发热、腹泻等不良副反应,其中强反应3例(0.73%),中度反应11例(2.68%),轻度反应4例(0.98%),均于对症治疗后3日内缓解并消失。临床资料证明,使用该疫苗是安全的。
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| 关 键 词： | 轮状病毒 口服活疫苗 安全性 |
| 文章编号： | 1005-5673（2006）03-0013-02 |
| 收稿时间： | 2006-05-22 |
| 修稿时间： | 2006年5月22日 |
The clinical observation on safety of Rotavirus vaccine (live), oral |
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| SHEN Guo-hong , XIN Qiang, YU Xiao-hong ,et al..The clinical observation on safety of Rotavirus vaccine (live), oral[J].Progress In Microbiology and Immunology,2006,34(3):13-14. |
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| Authors: | SHEN Guo-hong XIN Qiang YU Xiao-hong |
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| Institution: | 1 Jinan Central Hospital, Jinan, 250013, China; 2 The Disease Prevention and Control Center of Lixia Distract, Jinan ,250013, China |
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| Abstract: | To investigate the safety of Rotavirus vaccine(live),oral,we inoculated the vaccine to 410 children aged from 7 months to 3 years,who visited the Outpatient Department for vaccination in Jinan Central Hospital from April to October,2004 and the short-term outcome of the immunization was closely observed and recorded,including fever and other side effects.Most of the children,namely 95.61%(392/410),had no side effects at all,while 4.39%(18/410) were with some symptoms such as fever and diarrhea;3 of them(0.73%) were recognized as having a strong reaction,11(2.68%) of them were as a moderate,and another 4(0.98%) were with a weak reaction.All side effects disappeared in 3 days after routine treatment.Clinical results confirmed the safety of this oral live vaccine for RV. |
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| Keywords: | Rotavirus(RV) Live vaccine(oral) Safety |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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