| 成骨细胞中经典Wnt/β-catenin通路研究进展 |
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| 引用本文： | 许兵,刘慧,许应星,吴岩,肖鲁伟,童培建.成骨细胞中经典Wnt/β-catenin通路研究进展[J].生命科学,2011(5):477-481. |
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| 作者姓名： | 许兵 刘慧 许应星 吴岩 肖鲁伟 童培建 |
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| 作者单位： | 浙江中医药大学第一临床医学院;浙江省中医院骨伤科; |
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| 基金项目： | 卫生部科学研究基金(省部共建项目计划)(WKJ2008-2-032) |
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| 摘 要： | Wnt/β-catenin经典通路在成骨细胞的分化增殖中起着重要作用。目前研究表明,调节任何一个经典Wnt/β-catenin信号转导通路中的因子都能影响成骨细胞的分化增殖。总结经典Wnt/β-catenin通路中各个因子与成骨细胞分化增殖的关系,以便进一步具体深入研究经典Wnt/β-catenin通路对成骨细胞的影响。
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| 关 键 词： | 成骨细胞 Wnt/β-catenin 因子 |
Development of the classic Wnt/β-catenin pathway in osteoblasts |
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| XU Bing,LIU Hui,XU Ying-Xing,WU Yan,XIAO Lu-Wei,TONG Pei-Jian.Development of the classic Wnt/β-catenin pathway in osteoblasts[J].Chinese Bulletin of Life Sciences,2011(5):477-481. |
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| Authors: | XU Bing LIU Hui XU Ying-Xing WU Yan XIAO Lu-Wei TONG Pei-Jian |
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| Institution: | XU Bing1,LIU Hui1,XU Ying-Xing1,WU Yan1,XIAO Lu-Wei1,TONG Pei-Jian2*(1The First College of Clinic Medicine,Zhejiang Traditional Chinese Medical University,Hangzhou 310053,China,2 Orthopedics,Chinese Medicine Hospital of Zhejiang Province,Hangzhou 310012,China) |
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| Abstract: | The classical Wnt/β-catenin pathway plays an important role in the differentiation and proliferation of osteoblasts.Now the researches show that the regulation of any factors in classical Wnt/β-catenin signal transduction pathway can influence the differentiation and proliferation of osteoblasts.This paper summarizes the relationship between the respective factors in the classic Wnt/β-catenin pathway and the differentiation and proliferation of osteoblasts in order to further study the classical Wnt/β-catenin pathway of osteoblasts. |
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| Keywords: | osteoblast Wnt/β-catenin factor |
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