植物中参与活性氧调控的基因网络

植物体内活性氧（reactive oxygen species,ROS）是氧化还原反应的必然副产物,具极高的活性和毒性,从而对细胞产生毒害。同时,活性氧作为信号分子对很多生理过程诸如植物生长发育、细胞程序化死亡及生物和非生物胁迫应答起调控作用。植物中ROS双重作用的协调机制目前尚不明确,确定的是细胞中ROS维持于稳定水平需要精细的调节。拟南芥中至少包括152个基因组成的网络参与ROS的调控,该网络具高度的灵活性和互补性。本文综述了ROS网络中鉴定的一些关键基因及细胞学定位和协同作用,ROS信号转导,尤其是叶绿体中ROS信号的调控。

Reactive oxygen gene network of plants and its regulation

Reactive oxygen species(ROS) are inevitable by-products of biological redox reactions,they are highly reactive and toxic,and are capable of injuring cells.However,ROS also control many different processes in plants,such as growth,development,pathogen defense,programmed cell death,hormone signaling,biotic and abiotic stress responses and cell cycle as signaling molecules.How this conflict is resolved in plants is largely unknown.Nonetheless,it is clear that the steady-state level of ROS in cells needs to be tightly regulated.In Arabidopsis,a network of at least 152 genes is involved in managing the level of ROS.This network is highly dynamic and redundant,and encodes ROS-scavenging and ROS-producing proteins.This review discusses the cellular localization and coordination of key genes in the network,the regulation of ROS signaling by the reactive oxygen gene network in plant cell,especially in chloroplasts which are more prone to oxidative damage than any other organelle.