| 尾静脉注射和鼻腔接种禽流感H5N1亚型病毒对血细胞的影响 |
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| 引用本文： | 赵维波,张钰,闽凡贵,刘香梅,王静,刘忠华,黄韧.尾静脉注射和鼻腔接种禽流感H5N1亚型病毒对血细胞的影响[J].中国实验动物学报,2005(Z1). |
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| 作者姓名： | 赵维波 张钰 闽凡贵 刘香梅 王静 刘忠华 黄韧 |
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| 作者单位： | 广东省实验动物监测所 广州510260
(赵维波，张钰，闽凡贵，刘香梅，王静，刘忠华)，广东省实验动物监测所 广州510260(黄韧) |
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| 摘 要： | 目的]Balb/c小鼠通过尾静脉注射和鼻腔接种禽流感H5N1亚型病毒造疾病模型,观察其血细胞变化。方法]以禽流感H5N1亚型病毒通过静脉和鼻腔接种Balb/c小鼠,分别在0~7天和0~11天取血进行血细胞计数和分类,同时对于静脉接种方法进行了0~8小时的短时间监控。结果]静脉接种途径在接种病毒后2小时就能显著的降低小鼠的白细胞总数、粒细胞及淋巴细胞数,白细胞总数及淋巴细胞数在第3天、粒细胞数在第2天就恢复正常而后均显著升高;而鼻腔接种仅在1~3天淋巴细胞有所降低,而后恢复正常;1~6天白细胞总数及粒细胞数显著升高,而后恢复正常。结论]从血细胞变化而言,静脉接种相比鼻腔接种方法要好。
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Eff Blood Cell by Inoculated Intranasally and Inoculated Tail Vein with Influenza A (H5N1) Viruses |
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| Zhao Weibo,Zhang Yu,Ming Fangui,Liu Xiangmei,Wang Jing,Liu Zhonghua,Huang Ren GuangDong Laboratory Animals Monitoring Institute,GuangZhou.Eff Blood Cell by Inoculated Intranasally and Inoculated Tail Vein with Influenza A (H5N1) Viruses[J].Acta Laboratorium Animalis Scientia Sinica,2005(Z1). |
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| Authors: | Zhao Weibo Zhang Yu Ming Fangui Liu Xiangmei Wang Jing Liu Zhonghua Huang Ren GuangDong Laboratory Animals Monitoring Institute GuangZhou |
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| Institution: | Zhao Weibo,Zhang Yu,Ming Fangui,Liu Xiangmei,Wang Jing,Liu Zhonghua,Huang Ren GuangDong Laboratory Animals Monitoring Institute,GuangZhou,510260 |
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| Abstract: | |
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| Keywords: | Influenza A (H5N1) viruses leucocyte lymphocytee neutophilic granulocyte |
| 本文献已被 CNKI 等数据库收录！ |
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