健脾方抗衰老作用的实验研究

中医学认为肾气和脾胃虚衰是人衰老的主要原因之一,而益肾健脾胃为培原固本养生的重要治则。我们应用健脾的中西药组方分组进行老龄Wistar大鼠的实验冶疗。实验结果表明:健脾方能升高SOD(P<0.001),降低血清总胆固醇(P<0.05)增加HDL(г<0.001),和升高HDL/TC比值的作用,并且提高大鼠的耐乏氧(P<0.05)和抗疲劳(P<(?).01)的功能。维生素E则有升高SOD(P<(?).001)和HDL(г<0.001)并提高耐乏氧的作用。腔睥胃有抗衰老的功效。

The Experimental Study on the Anti-Senility Effect of Spleen Strengthening Recipe ( SSR )

Sixty-six old rats were divided into 22 blocks by randomized block design.Three rats in each block were randomized into group SSR ( fed on feed containing SSR; white atractylodes rhizome. poria, ginseng, medicated leaven, tangerine peel, amomum fruit germinated barley, haw thorn fruit, Chinese yam, nutmeg, aucklandia root, astragalus root, and liquorice), group vit.E(fed on feed containing vit.E) , and control group ( fed on basic feed only) . After 90 days'feeding, the differences among 3 groups were compared by the following values:on rats in blocks 1-22,the differences of superoxide dismutase ( SOD ) , serum total cholesterol ( TC), high-density lipoprotein (HDL), and low-density lipoprotein ( LDL ) before and after experiments; on rats in blocks 1-11, the ability to resist fatigue; and on rats in blocks 12-22, the ability to tolerate hypoxia. The results showed: SSR had effects of raising SOD ( P<0.001 ) , lowering TC(P<0.05), and increasing HDL ( P<0.001) ,and a tendency to raise the ratio of HDL/ TC, and also could promote the ability of hypoxia tolerance ( P<0.05 ) , and fatigue resistance ( P<0.01)in old rats.Vit.E had effects of increasing SOD(P<0.001) , and HDL ( P<0.001 ) . and could promote the ability,of hypoxia tolerance(P<0.01)in old rats.Hence ,the objective of strengthening the spleen and stomach to counteract senility has been further proved, and experimental evidence has been provided for the theory that a healthy spleen and stomach would lead to "chang you tian ming" ( longevity ) .