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硝酸士的宁对刺激鲫鱼脊髓诱发的Mauthner细胞胞内电位变化的影响
引用本文:虞棻,童学红,李博,刘丽敏,张茂先,李效义.硝酸士的宁对刺激鲫鱼脊髓诱发的Mauthner细胞胞内电位变化的影响[J].中国实验动物学报,2008,16(6):449-451.
作者姓名:虞棻  童学红  李博  刘丽敏  张茂先  李效义
作者单位:首都医科大学生理学系,北京,100069
摘    要:目的探索肌注硝酸士的宁对刺激鲫鱼脊髓所诱发的M细胞胞内电位变化的影响。方法运用微电极穿刺技术记录M细胞的胞内电位变化。结果肌注硝酸士的宁后逆向动作电位后突触后电位(PSPs)的幅度升高,持续时间增加,并可在此基础上暴发动作电位。结论从脊髓到M细胞的传入通路中可能有抑制性递质甘氨酸的释放和相应受体的存在,其与兴奋性递质一起调节M细胞兴奋性,从而使M细胞的活动与整体一致。

关 键 词:Mauthner细胞  士的宁  突触后电位  鲫鱼

Effects of Intramuscular Injection of Strychnine on the Intracellular Potential Changes of Mauthner Cells Evoked by Spinal Cord Stimulation in Crucian Carps
YU Fen,TONG Xue-hong,LI Bo,LIU Li-min,ZHANG Mao-xian,LI Xiao-yi.Effects of Intramuscular Injection of Strychnine on the Intracellular Potential Changes of Mauthner Cells Evoked by Spinal Cord Stimulation in Crucian Carps[J].Acta Laboratorium Animalis Scientia Sinica,2008,16(6):449-451.
Authors:YU Fen  TONG Xue-hong  LI Bo  LIU Li-min  ZHANG Mao-xian  LI Xiao-yi
Institution:YU Fen,TONG Xue-hong,LI Bo,LIU Li-min,ZHANG Mao-xian,LI Xiao-yi(Department of Physiology,Capital Medical University,Beijing 100069,China)
Abstract:Objective To explore the intracellular potential changes of Mauthner cells(M-cells)evoked by spinal cord stimulation in the Crucian carp after intramuscular injection of strychnine.Methods\ Microelectrode recording technique was used to explore the electrophysiological properties of M-cells.Results\ Both the amplitude and the average duration of the postsynaptic potential(PSP) in M-cells were increased,and two or more action potentials were sometimes superimposed.Conclusion\ The results suggest that there a...
Keywords:Mauthner cell  Strychnine  PSPs  Crucian carp  
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