Detection of lateral gene transfer among microbial genomes |
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| Authors: | Mark A Ragan |
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| Institution: | Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland 4072, Australia. m.ragan@imb.uq.edu.au |
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| Abstract: | An increasingly comprehensive assessment is being developed of the extent and potential significance of lateral gene transfer among microbial genomes. Genomic sequences can be identified as being of putatively lateral origin by their unexpected phyletic distribution, atypical sequence composition, differential presence or absence in closely related genomes, or incongruent phylogenetic trees. These complementary approaches sometimes yield inconsistent results. Not only more data but also quantitative models and simulations are needed urgently. |
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| Keywords: | Lateral gene transfer horizontal gene transfer comparative genomics microbial genomics surrogate methods phylogenomics |
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