Assignment of the fucosidase pseudogene FUCA1P to chromosome region 2q31----q32 |
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Authors: | P Coucke K Mangelschots F Speleman P Bossuyt P Van Oostveldt B Van der Auwera B Carritt P J Willems |
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Institution: | Department of Medical Genetics, University of Antwerp-U.I.A., Belgium. |
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Abstract: | FUCA1P is a pseudogene of the structural fucosidase gene FUCA1. The former has been mapped to human chromosome 2, whereas the latter has been localized to chromosome 1p34----p36. We have further localized FUCA1P to chromosomal band 2q31----q32 by fluorescent in situ hybridization and digital imaging microscopy. This localization was confirmed by linkage analysis between FUCA1P and the COL3A1 gene in 2q24----q32 which gave maximal lod scores of 4.03 at 3% recombination. |
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