| 西藏拉萨地区藏族儿童血红蛋白类型和一例血红蛋白E的化学结构分析 |
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| 引用本文： | 宋良权,郑元明,葛向明,陈星林,叶如陵,冯尚文,陈松森,敖朝晖,贾佩臣,梁植权.西藏拉萨地区藏族儿童血红蛋白类型和一例血红蛋白E的化学结构分析[J].中国生物化学与分子生物学报,1989,5(5):433-435. |
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| 作者姓名： | 宋良权 郑元明 葛向明 陈星林 叶如陵 冯尚文 陈松森 敖朝晖 贾佩臣 梁植权 |
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| 作者单位： | 西藏自治区人民医院 拉萨
(宋良权，郑元明，葛向明，陈星林，叶如陵，冯尚文)，中国医学科学院基础医学研究所 北京
(陈松森，敖朝晖，贾佩臣)，中国医学科学院基础医学研究所 北京(梁植权) |
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| 摘 要： | 本文报道480例西藏拉萨地区藏族儿童的血红蛋白类型,除发现一例慢速β链Hb变异体之外,其余均无异常。对该异常者Hb的化学结构进行分析,确证为HbEβ~(26(B8))Glu→Lys]。此为我国藏族人群中首次发现。
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| 关 键 词： | 藏族儿童 血红蛋白 高效液相层析 血红蛋白E |
| 收稿时间： | 1989-10-20 |
Hemoglobin Types of the Tibetan Children of Lhasa,Tibet and the Structural Analysis of a Case of Hemoglobin E |
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| Song,Liang-chuan Zhen,Yuan-ming Ge,Xang-ming Chen,Xing-ling Ye,Ru-ling Fen,Shang-weng.Hemoglobin Types of the Tibetan Children of Lhasa,Tibet and the Structural Analysis of a Case of Hemoglobin E[J].Chinese Journal of Biochemistry and Molecular Biology,1989,5(5):433-435. |
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| Authors: | Song Liang-chuan Zhen Yuan-ming Ge Xang-ming Chen Xing-ling Ye Ru-ling Fen Shang-weng |
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| Institution: | (The People's Hospital of Tibet Autonomus Region, Lasa)Chen, Song-shen Ao, Zhao-hui Ja, Pei-chen Liang, Chih-chuan (Institute of Basic Med. Sci., Academy of Medical Sciences, Beijing |
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| Abstract: | The hemoglobin types of 480 cases of 11-15 years old Tibetan children were studied.The results showed that all cases were normal except one case. Structural analysis by high perfornance liquid chromatography (HPLC) showed that this abnormal case was Hb E (β28(B8)Glu→Lys), which was the first case found in Lhasa, Tibet. |
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| Keywords: | Tibetan children Hemoglobin HPLC Hb E |
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