阿的平对热环境中行军战士血液某些生化指标的影响

利用比色法、竞争性蛋白结合技术及放射性免疫分析法，分析热环境中负重行军战士血液乳酸含量、ｃＡＭＰ、ｃＧＭＰ及皮质醇含量，以探讨热应激过程中机体的生化变化特点，并观察阿的平对这些变化的影响。结果表明：行军后战士血液乳酸浓度、皮质醇含量（２．０８±０．１８ｍｍｏｌ／Ｌ、１６．２５±１．０５μｇ／１００ｍＬ）较行军前（１．６２±０．１６ｍｍｏｌ／Ｌ、１４．９８±０．９μｇ／１００ｍＬ）明显升高，而行军后血浆ｃＡＭＰ浓度（１８．８±３．９ｐｍｏｌ／ｍＬ）则较行军前（３２．９±６．０ｐｍｏｌ／ｍＬ）显著降低，ｃＧＭＰ在行军前后无明显变化；行军前预服阿的平，具有减弱或逆转上述变化的作用。

The Effect of Quinacrine on Blood Biockemical Parameters of Soldiers Marching with Load in Hot Environment

Contents of blood lactic acid, cAMP, cGMP and cortisol of soldiers marching with load in hot environment were determined by colorimetry, competitive protein-binding technique and radioimmunoassay (RIA) respectively. The experimental results showed as follows (1) the contents of blood lactic acid and cortisol (2.08±0.118mmol/L and 16. 25±1.05μg/100mL respectively) after marching showed a marked increase compared with that of before marching (1.62±0.16mmol/L and 14.98±0.9μg/100ml respectively); (2) the contents of blood cAMP (18.8±0.9μg/mL) after marching decreased markedly in comparison with values before marching (32.9±6. 0μg/mL), but there has been no change in contents of blood cGMP after marching when compared with values before marching; (3) the changes mentioned above could be restrained by administering quinacrine before marching.