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Three-dimensional distribution of Ag-NOR proteins in rat superior cervical ganglia nucleoli according to circadian rhythm
Authors:Pébusque  M J  Dupuy-Coin  A M  Seite  R  Bouteille  M  Moens  P
Institution:(1) Faculté de Médecine, Groupe de Neurocytobiologie, Laboratoire de Biologie Cellulaire et Tissulaire, 27 Boulevard J. Moulin, F-13385 Marseille Cedex 5, France;(2) Laboratoire de Pathologie Cellulaire, Institut Biomédical des Cordeliers, 15 Rue de l'Ecole de Médecine, F-75270 Paris Cedex 6, France;(3) Department of Biology, York University, Downsview, Ontario, Canada
Abstract:A three-dimensional reconstruction of the distribution of Ag-NOR proteins in nucleoli of sympathetic neurons of a rat killed during the dark period of its light-dark cycle was compared with previously reported analyses on the three-dimensional distribution of fibrillar centers, the high-resolution localization of these proteins, and the morphometric results. The domain occupied by these proteins appeared to far exceed that of the fibrillar centers and included the dense fibrillar RNP component. In the present material this component in turn provided partial bridging between the units consisting of the fibrillar centers plus their surrounding dense fibrillar component.
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